D-二聚体
医学
C反应蛋白
内科学
2019年冠状病毒病(COVID-19)
白细胞
胃肠病学
淋巴细胞
血小板
严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)
免疫学
炎症
疾病
传染病(医学专业)
作者
Hamide Shllaku-Sefa,Gentian Kasmi,Irena Kasmi,Emmanuel Eragbe Sule,Ndok Marku
出处
期刊:Clinical Laboratory
[Clinical Laboratory Publications]
日期:2023-01-01
卷期号:69 (08/2023)
标识
DOI:10.7754/clin.lab.2023.221102
摘要
The main goal of this study is to evaluate correlations between D-dimer, C-reactive protein (CRP), and hematologic data in outpatients with COVID-19. We also aimed to assess if the correlations found for hospitalized patients can be applied to outpatients.We performed a retrospective study including 100 outpatients, 51 women and 49 men, mean age 51 ± 15 years, from August 2020 to January 2022, diagnosed positive with COVID-19 by real time RT-PCR or rapid antigens test.The most affected age group with COVID-19 was 51 - 60 years with 29%, whereas 73% of outpatients were less than 60 years. Hematologic data in most outpatients were normal, only 23% of them had an increased neutrophil to lymphocyte ratio (NLR) and 22% had decreased the lymphocyte count. Regarding inflammatory parameters 42% had CRP above the reference range and only 22% had an increased value of D-dimer. We have found correlations between D-dimer and CRP (r = 0.39, p < 0.02). CRP and WBC (r = 0.42, p < 0.011), CRP and NLR (r = 0.73, p < 0.001). White blood cells (WBC) and NLR (r = 0.58, p < 0.001), WBC and platelets (r = 0.45, p < 0.004).We conclude that the correlations found between the variables studied are found to be present in outpatients and therefore they can serve as good markers to decide whether further tests need to be performed for the diagnosis of severe cases and prognosis of COVID-19.
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