Functions and mechanisms of nonstarch polysaccharides in monogastric animal production

As natural active ingredients, polysaccharides are a class of biological macromolecules that are ubiquitous in living organisms and have antibacterial, antioxidant, antitumor and intestinal flora-regulating functions. Nonstarch polysaccharides (NSPs) are an important class of polysaccharides that include both soluble and insoluble nonstarch polysaccharides. As green feed additives, NSPs play important roles in promoting immunity and disease resistance in the body, regulating the intestinal microbial balance and improving the quality of animal products. NSPs regulate cell signal transduction mainly via interactions between short-chain fatty acids and G protein-coupled receptors and inhibiting the histone deacetylation pathway to protect the intestinal barrier in animals. In this paper, the composition, physiological functions, and molecular mechanisms of the gut protective effects of NSPs are reviewed to provide a reference for the application of NSPs in monogastric animal production.