Kidney Insights

医学 泌尿科
作者
Peter Stenvinkel,Paul G. Shiels,Peter Kotanko,Pieter Evenepoel,Richard J. Johnson
出处
期刊:Journal of The American Society of Nephrology
标识
DOI:10.1681/asn.0000000582
摘要

Planetary health encompasses the understanding that the long-term well-being of humanity is intrinsically linked to the health of global ecological systems. Unfortunately, current practices often overlook this principle, leading to a human-oriented (anthropocentric) worldview that has resulted in heightened greenhouse gas emissions, increased heat stress, lack of access to clean water and pollution, threatening both the environment and the health and survival of Homo sapiens and countless other species. One significant consequence of these environmental changes is the exacerbation of inflammatory and oxidative stressors, which not only contributes to common lifestyle diseases, but also accelerate the aging process. We advocate for a shift away from our current anthropocentric frameworks to an approach that focuses on nature's solutions that developed from natural selection over the eons. This approach, which encompasses the field of biomimicry, may provide insights that can help protect against an 'inflammatory phenotype' to mitigate physiological and cellular senescence and provide a buffer against environmental stressors. Gaining insights from how animals have developed ingenious approaches to combat adversity through the evolutionary process of natural selection not only provide solutions for climate change, but also confronts the rising burden of lifestyle diseases that accumulate with age.

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