Posterior cortical atrophy: new insights into treatments and biomarkers for Alzheimer's disease

Alzheimer's disease typically manifests with impairment of episodic memory, followed by gradual deterioration of other cognitive functions. However, the disease is heterogeneous, and some people have atypical presentations, such as predominant visual, language, executive, behavioural, or motor dysfunction. The visual variant, also known as posterior cortical atrophy or Benson syndrome, is characterised by a progressive decline in basic visual, visuoperceptual, literacy, praxis, numeracy, and higher sensory functions.