The relationship between serum and liquor IL-1β, IL-6, TNFa, IL-10 levels and clinical, cognitive and functional characteristics in acute ischemic stroke

Despite the antagonistic effects of IL-1β, IL-6 and IL-10 on inflammation, associations of these cytokines with anamnestic, clinical, neuropsychological and functional characteristics were similar in acute ischemic stroke. Probably, this fact indicates that during the acute ischemic brain damage process the immune response develops at the same time in pro- and anti-inflammatory directions. Its magnitude correlates with the damage severity and is associated with the effects of vascular risk factors before stroke.