ABSTRACT 548

Background and aims: Central venous catheters (CVC) although very useful are frequently associated with several complications. Aims: To estimate the incidence and characterize risk factors for CVC related deep vein thrombosis (DVT) and develop a risk assessment tool to be used for generation of venous thromboembolism (VTE) prophylaxis guidelines. Methods: Retrospective chart review of all patients with percutaneous short term CVCs admitted in PICU from September 2012 to August 2013. A pre-defined proforma was filled out for each CVC inserted to look for development of CVC related DVT and to identify common risk factors associated with it. Results: A total of 215 CVCs were inserted into 156 patients. The incidence of CVC related DVT was 6% (13 of 215) all of which involved femoral CVCs. Risk factors most predictive of CVC related DVT were age < 2 or >14 years, immobility for >72 hours, line infection and hypercoagulable states such as DKA. The risk assessment score in children with DVT was 2 ± 1.4. Conclusions: The frequency of CVC related DVT is substantial in PICU patients. We have identified high risk factors associated with this and devised a score which will be helpful for future generation of VTE prophylaxis guidelines to help prevent this serious complication of CVC use.