医学
肥胖
体脂分布
体质指数
脂肪组织
疾病
肥胖的分类
流行病学
分布(数学)
脂肪团
内科学
生物信息学
内分泌学
生理学
生物
数学分析
数学
作者
Marie-Éve Piché,Paul Poirier,Isabelle Lemieux,Jean‐Pierre Després
标识
DOI:10.1016/j.pcad.2018.06.004
摘要
Obesity is recognized as a heterogeneous condition in which individuals with similar body mass index may have distinct metabolic and cardiovascular risk profiles. Susceptibility to obesity-related cardiometabolic complications is not solely mediated by overall body fat mass, but is largely dependent upon individual differences in regional body fat distribution and ability of subcutaneous adipose tissue to expand. The present review will discuss to what extent the individual variation in body fat distribution is one of the clinical key variables explaining the metabolic heterogeneity of obesity and its related cardiovascular risk. We will present the evidence for the complex nature of the relationship between obesity and cardiovascular disease, outline our current understanding of the mechanisms involved, and identify future direction of research pertinent to this interaction.
科研通智能强力驱动
Strongly Powered by AbleSci AI