Classification of Hypersensitivity in Relation to Clinical Disease

Review1 March 1966Classification of Hypersensitivity in Relation to Clinical DiseaseGUNNAR BENDIXEN, M.D.GUNNAR BENDIXEN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-3-668 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe word hypersensitivity in this paper indicates a state of specifically altered reactivity depending on an antigen-antibody reaction. According to this definition hypersensitivity covers a wide range of conditions corresponding to the concept of allergy as proposed by von Pirquet (1). As the word allergy has gradually lost its specific significance, it will not be used here.To evaluate diseases in which mechanisms of hypersensitivity are in action, a correct understanding of the nature of hypersensitive phenomena is necessary. 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