化学
芳基
三氟甲基
氯化物
药物化学
有机化学
烷基
作者
Gerhard Simchen,Andreas Schmidt
出处
期刊:Synthesis
[Thieme Medical Publishers (Germany)]
日期:1996-09-01
卷期号:1996 (09): 1093-1094
被引量:23
摘要
A Simple Method for the Preparation of Aryl Trifluoromethyl Ketones. Caret4-Dimethylamino-1-trifluoroacetylpyrimidinium trifluoroacetate (2) is an effective, easy to handle and stable trifluoroacetylationagent. Aryl trifluormethyl ketones 4 are obtained in good yieldsby reaction of 2 with aromatic compounds 3 in thepresence of aluminum chloride.
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