Study on the switching points of sequential mechanical ventilation in the treatment of severe respiratory failure due to COPD

Objective To investigate the switching points of sequential mechanical ventilation in the treatment of severe respiratory failure due to COPD.Methods Sixty-four patients of severe respiratory failure due to chronic obstructive pulmonary disease(COPD) were randomly divided into the study group and the group,each with 32 cases.Patients in the two groups were treated with synchronized intermittent mandatory+PSV+PEEP,but using Glasgow Coma Scale as a switching time windows in the study group and using lung infection under control as the time windows in the group patients.Results Before extubation,the blood gas analysis,respiratory rate,heart rate,pH showed no statistically significant difference between the two groups(P0.05).And the blood gas analysis,respiratory rate,heart rate,pH after extubation,in the two groups showed no statistically significant difference with those before extubation(P 0.05).In the study group,the time of invasive mechanical ventilation,the total mechanical ventilation time,length of hospital stay was significantly less than those in the group,with the incidence of VAP significantly lower(P0.05).Conclusion For treating severe respiratory failure with COPD,Glasgow Coma Scale assessment as switching time windows in sequential mechanical ventilation can significantly improve the therapeutic effect.