[Research advances on application of botulinum toxin type A in scar prevention and treatment].

The wound healing time, tension of wound edge, proliferation of fibroblast, and extracellular matrix deposition are the important factors of scar formation, and botulinum toxin type A can regulate the above. Prevention and treatment of scar with botulinum toxin type A is one of the hot topics of clinical research in recent years. This paper briefly reviews researches by scholars at home and abroad on the mechanism, clinical application, complications, and adverse effects of botulinum toxin type A in scar prevention and treatment.创面愈合的时间、创缘张力、成纤维细胞增殖和细胞外基质的沉积是瘢痕形成的重要原因，而A型肉毒毒素可在以上多个方面进行调控。A型肉毒毒素应用于瘢痕防治是近年来临床研究的热点之一。该文就国内外学者对A型肉毒毒素在瘢痕防治中的作用机制、临床应用及应用中产生的并发症和不良反应的相关研究进行简要综述。.