医学
癌胚抗原
毒性
皮疹
免疫疗法
嵌合抗原受体
癌症研究
细胞因子
细胞因子释放综合征
免疫学
不利影响
化疗
受体
抗原
肿瘤科
安全概况
作者
Zhuo Xiang,Guilai Chen,Li Yin,Xiaozhi Xi,Tangnuran Halimulati,Xiaofeng Yu,Qingqing Wang,Qingqing Wang,Qingwen Wang,Qingwen Wang,Jingwang Bi,Qiang Wang,Jingwang Bi,Qiang Wang,Qiang Wang
摘要
Cutaneous toxicity following CAR-T therapy is closely linked to immune-cell subset expansion and cytokine dynamics. Prophylactic H1-antihistamines showed effective prevention of rash development, thereby improving the safety profile in solid tumour CAR-T therapy.
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