Migraine is the second most common cause of headache and has a significant impact on a persons quality of life. Available modes of treatment largely focus on pain management. Homoeopathy offers a comprehensive solution to migraine patients providing not only pain relief but also a reduction in frequency and intensity of episodes and a hope for a migraine-free life. This case report presents utility of Homoeopathic medicine Natrum muriaticum in reducing pain and episodes of migraine.