伤口愈合
一氧化氮合酶
蛋白激酶B
炎症
细胞生物学
细胞迁移
角膜
信号转导
化学
促炎细胞因子
角膜上皮
癌症研究
PI3K/AKT/mTOR通路
一氧化氮
药理学
免疫学
细胞
医学
生物
眼科
生物化学
有机化学
作者
Ziwen Sun,Kunpeng Lu,Qing He,Yang Tang,H. Li,Emmanuel Eric Pazo,Lizhi Hu,Ruihua Wei
标识
DOI:10.1016/j.exer.2024.109886
摘要
Corneal injury leads to impaired normal structure of the cornea. Improving the wound healing process in epithelial cells significantly contributes to ocular damage treatments. Here, we aimed to investigate the potential mechanisms of nitric oxide (NO) and its mediator, inducible nitric oxide synthase (iNOS), in the process of corneal wound healing. We established a corneal injury model of iNOS
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