Erythrocyte Transfer RNA: Change during Chick Development

Radioactive aminoacyl transfer RNA's isolated from erythrocytes in the blood of 4-day-old chick embryos and from reticulocytes of adult chickens were analyzed by chromatography on methylated albumin kieselguhr and freon columns. Embryonic and adult methionyl transfer RNA's showed qualitative and quantitative differences in both chromatographic systems. The patterns for arginyl, seryl, and tyrosyl transfer RNA's in the two cell types were similar, while the leucyl transfer RNA patterns suggested a difference.