医学
普拉克索
左旋多巴
临床试验
内科学
罗替戈汀
耐受性
作者
Charles H. Adler,Robert A. Hauser,Kapil D. Sethi,John N. Caviness,L. Marlor,William J. Anderson,Joseph G. Hentz
出处
期刊:Neurology
[Ovid Technologies (Wolters Kluwer)]
日期:2004-04-26
卷期号:62 (8): 1405-1407
被引量:98
标识
DOI:10.1212/01.wnl.0000120672.94060.f1
摘要
The authors performed a double-blind, placebo-controlled, crossover study of ropinirole (0.5 to 6.0 mg/day) for restless legs syndrome (RLS). The RLS Rating Scale score improved (p < 0.001) from a mean (SD) of 25 (7) during placebo treatment to 13 (12) during ropinirole treatment. Eight of the 22 patients had complete resolution of symptoms on ropinirole. Adverse events included nausea and dizziness. Ropinirole was effective and well tolerated for treating the symptoms of RLS.
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