Inhibition of Escherichia coli adhesion to cell by Echinacea polysaccharide.

Objective To study the effection of Echinacea polysaccharide(EP) on Escherichia coli adhesion to cell.Method Adhesion test and inhibiting adhesion test were carried out on PK-15 cell.Result EP had the best inhibition for E.coli adhesion to PK-15 cell at 1.6 mg/ml concentration,the number of bacteria adhesion to cells were reduced from 50 per cell to 6.8 per cell.Conclusion The cell adhesion of E.coli can be inhibited by EP,which may have the potential application value in regulating of gut microflora.