Abstract 13836: Accessory Renal Arteries Perfuse a Substantial Fraction of Renal Mass: Studies in Renal Denervation Patients

Introduction: Renal denervation is an emerging therapy for resistant hypertension, but has a non-response rate of roughly 15-30%. Untreated accessory renal arteries may have a potentially causative role in non-response. Prior data show a strongly proportional relationship between individual renal mass and cross sectional area of the principal artery perfusing that kidney, analogous to the relations between myocardial mass and coronary artery area. Because accessory renal arteries are prevalent (up to 65%) in patients undergoing renal denervation, we questioned whether accounting for their presence would further strengthen the correlation between renal mass and artery cross sectional area. Methods: High resolution CT scans from 34 participants in the REDUCE-HTN Clinical study were measured for kidney volume and main renal artery area (TRAA). Areas of all visible accessory arteries were measured separately. Standard linear regression was used to determine the quantitative relationship among these parameters...