Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis
医学
他汀类
糖尿病
内科学
物理疗法
荟萃分析
医学诊断
内分泌学
病理
作者
Christina Reith,David Preiss,Lisa Blackwell,Jonathan Emberson,Enti Spata,Kelly Davies,Heather Halls,Charlie Harper,Lisa Holland,Kate Wilson,Alistair Roddick,Christopher P. Cannon,Robert Clarke,Helen M. Colhoun,Paul N. Durrington,Shinya Goto,G. A. Hitman,G. Kees Hovingh,J. Wouter Jukema,Wolfgang Köenig
Previous meta-analyses of summary data from randomised controlled trials have shown that statin therapy increases the risk of diabetes, but less is known about the size or timing of this effect, or who is at greatest risk. We aimed to address these gaps in knowledge through analysis of individual participant data from large, long-term, randomised, double-blind trials of statin therapy.