FGF21型
医学
车站3
盐皮质激素受体
心力衰竭
心肌梗塞
螺内酯
肝细胞
内科学
心脏病学
SOCS3
内分泌学
STAT蛋白
GDF15型
受体
信号转导
成纤维细胞生长因子
生物
细胞生物学
生物化学
体外
作者
Jianyong Sun,Lin‐Juan Du,Xuerui Shi,Yuyao Zhang,Yuan Liu,Yong-Li Wang,Bo‐Yan Chen,Ting Liu,Hong Zhu,Yan Liu,Cheng‐Chao Ruan,Zhenji Gan,Hao Ying,Zhinan Yin,Pingjin Gao,Xiaoxiang Yan,Ruogu Li,Sheng‐Zhong Duan
出处
期刊：Science Advances
[American Association for the Advancement of Science]
日期：2023-04-05
卷期号：9 (14)
被引量：36
标识
DOI：10.1126/sciadv.ade4110
摘要
The liver plays a protective role in myocardial infarction (MI). However, very little is known about the mechanisms. Here, we identify mineralocorticoid receptor (MR) as a pivotal nexus that conveys communications between the liver and the heart during MI. Hepatocyte
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