Novel Chalcone Derivatives Containing Pyrazole: Synthesis, Antifungal Activity Evaluation, and Mechanism of Action against Phomopsis sp.

disrupted the fullness of the pathogenic fungal membrane, causing the cell membrane to curve, fork, and fold and affecting the normal growth of mycelium. Further studies found that the change of membrane integrity of pathogenic fungi led to the leakage of cytoplasmic contents and the increase of malondialdehyde (MDA) content.