Ir-f-Amphbinol-Catalyzed Asymmetric Hydrogenation of N -Protected α-Amino Ketones Followed by Deprotection for Preparation of β-Primary Amino Alcohols

and applied them to the efficient iridium-catalyzed asymmetric hydrogenation of various ketones. Based on the literature reports and our experimental results, we further proposed a possible ONa/MH instead of NNa/MH bifunctional mechanism.