血管收缩
医学
内科学
胰岛素抵抗
糖尿病
2型糖尿病
胰岛素
内分泌学
动脉硬化
血管平滑肌
心脏病学
血压
平滑肌
作者
Linda Jahn,Lee M Hartline,Amanda J Kleiner,William B. Horton,Farhad Hasan,Alvin Wai Kit Tan,Zhenqi Liu,Eugene J. Barrett
出处
期刊:American Journal of Physiology-endocrinology and Metabolism
[American Physiological Society]
日期:2023-05-01
卷期号:324 (5): E402-E408
被引量:1
标识
DOI:10.1152/ajpendo.00242.2022
摘要
Using contrast ultrasound and measures of vascular stiffness, we compared vascular and metabolic responses to insulin in patients with type 1 diabetes with age-matched controls. The patients with type 1 diabetes demonstrated both vascular and metabolic insulin resistance with more than half of the patients with diabetes having a paradoxical vasoconstrictive vascular response to insulin.
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