Potential Disease-Modifying Treatment Strategies Targeting Senescence in the Setting of Knee Osteoarthritis

the knee joint is a very common site for osteoarthritic pain given the high use and stress subjected to the joint daily [7].Several important risk factors are associated with OA onset including but not limited to BMI, previous knee injury, age, gender, family history [8].OA can be generally categorized into two groups: idiopathic (age-associated OA, AAOA) and secondary, which is