Antibacterial application and toxicity of metal–organic frameworks

Metal–organic frameworks (MOFs), which are also referred to as coordination polymers, have been widely used in adsorption separation and catalysis, especially in the field of physical chemistry in the past few years, because of their unique physical structure and potential chemical properties. In recent years, particularly with the continuous expansion of the research field, deepening of research levels, and sustained advancements in science and technology, powerful and diverse MOFs that have demonstrated great biomedical application potential have been successively developed. Consequently, this study summarizes the origin, development, and common synthesis methods of MOFs, with major emphasis on their antibacterial application and safety evaluation in biomedicine.