B(C6F5)3‐Catalyzed Cascade Reduction of Pyridines

Abstract B(C 6 F 5 ) 3 has been found to be an effective catalyst for reduction of pyridines and other electron‐deficient N‐heteroarenes with hydrosilanes (or hydroboranes) and amines as the reducing reagents. The success of this development hinges upon the realization of a cascade process of dearomative hydrosilylation (or hydroboration) and transfer hydrogenation. The broad functional‐group tolerance (e.g. ketone, ester, unactivated olefins, nitro, nitrile, heterocycles, etc.) implies high practical utility.