Penumbral salvage and thrombolysis outcome: a drop of brain, a week of life

taken together with other modelsgenomic predictive models, detailed simulation models, statistical models-along with clinical judgement, to determine a treatment plan.The clinician will run BNMs with perturbations that correspond to possible surgical options, including removal of all or parts of the epileptogenic zone, partial removal of parts of the propagation zone, tractotomies dividing parts of the epileptogenic zone or dividing epileptogenic zone from propagation zone, etc.This will provide plans for cure based on surgeries (or non-invasive ablations) that cannot currently be proposed.How can the Virtual Brain help us understand the real one?Brain oscillations are thought to furnish the underpinnings of perception, motivation, thought and consciousness via mechanisms of firing synchronies creating representations.The Virtual Brain recreates some of these dynamics and can potentially explain how these oscillations permit area-toarea synchronies, as well as how these dynamics are disturbed to create seizures and to produce various movement disorders.The four activity state variables x 1 , y 1 , x 2 , y 2 can be grossly mapped onto the activity of underlying excitatory-inhibitory