The authors studied serum phospholipid subunits in patients with anthracosilicosis associated with vibration disease. Findings are significantly higher detergent fraction of phospholipids--lysophosphatidylcholine, phosphatidylserine, sphingomyelin, lower phosphatidylcholine, phosphatidylethanolamine and phosphoinositides--that suggests increased transmissivity of biologic membranes and activated inosite mechanism of transmembrane signal transmission. Aeroionization appeared to have positive influence, normalizing serum phospholipids level.