拟南芥
代谢组学
拟南芥
类黄酮生物合成
计算生物学
次生代谢
生物
植物代谢
生物合成
化学
转录组
生物化学
基因
生物信息学
基因表达
突变体
核糖核酸
作者
Ryo Nakabayashi,Mami Yamazaki,Kazuki Saito
标识
DOI:10.1016/j.nbt.2010.03.004
摘要
The sequencing of the entire genome of model plants has made it possible to use these plants for producing metabolites that are beneficial to humans. Plants produce a large number of metabolites, which are potentially valuable sources of novel pharmaceutically active agents that benefit human health. The industrial use of these beneficial metabolites from plants, known as secondary metabolites or specialized metabolites, necessitates the systematic understanding of the biosynthetic mechanisms from the genetic to the metabolic level. Here, we review the recent developments on flavonoid biosynthesis in Arabidopsis thaliana (Arabidopsis) as a model plant. These developments have been made in the fields of metabolomics, transcriptomics, natural products chemistry, genetics and biochemistry. We focused on natural products chemistry in this polyhedral approach, which proved to be indispensable for elucidating the secondary metabolism in not only Arabidopsis but also other model-like and crop plants.
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