Radiofrequency ablation: time to think of poor responders

Since its first description in 2004 by Ganz et al. [1], radiofrequency ablation (RFA) has become the standard treatment of flat dysplastic Barrett’s esophagus (BE) after endoscopic resection of all visible lesions. Compared with alternative eradication methods, such as stepwise endoscopic resection, (hybrid) argon plasma coagulation, and cryoablation, RFA is the best validated and most used ablation method that is both effective and relatively safe, and is unanimously recommended by various guidelines.