Null Hypothesis for Clinically Relevant Effects

Background: Statistical significance testing (SST) has been serving the important purpose of advancement of research in all walks of life. Researchers utilize the statistical significance testing for illustrating the importance of their research findings. Statistical significance has become a rigidly defined and enforced criterion for the publication of research in most of the scientific journals. The journals accept manuscript documenting findings with details on study design, sample size, methods of statistical analysis, and statistical significance of research findings.