Natural therapy proposed for the management of diabetic peripheral neuropathy (DPN)

Abstract Approximately 50% of patients with diabetes mellitus (DM) are known to have significant side effects, including retinopathy, cardiomyopathy, peripheral neuropathy, and nephropathy. Most of these complications are caused by inadequate glycemic control or incorrect pathology management. In any event, diabetic peripheral neuropathy (DPN) appears to be the most common and painful consequence that many DM patients experience. As a result, this review aimed to gather the wide range of treatments used to manage DPN, beginning with the most traditional therapy and progressing to alternative approaches. Medicinal plants and their bioactive compounds have been widely used as natural medicines for various diseases, with little known adverse effects. This review emphasizes the role of medicinal plants and their naturally occurring bioactive components in combating this condition.