医学
支气管肺发育不良
重症监护医学
呼吸保健
呼气
呼吸系统
通风(建筑)
麻醉
内科学
怀孕
胎龄
机械工程
遗传学
工程类
生物
作者
George Ferzli,Maria Jebbia,Audrey N. Miller,Leif D. Nelin,Edward G. Shepherd
标识
DOI:10.1016/j.semperi.2023.151816
摘要
Respiratory management of infants with established severe BPD is difficult and there is little evidence upon which to base decisions. Nonetheless, the physiology of severe BPD is well described with a predominantly obstructive pattern. This pulmonary dysfunction results in prolonged exhalatory time constants and thus ventilator management must be focused on maintaining adequate oxygenation and ventilation through achieving full exhalation. This approach is often difficult to maintain in acute care settings and a culture of chronic care focused on slow change and steady progress is imperative. Once respiratory stability is achieved, the focus should shift to growth and development and avoidance of care practices and medications that impair neurodevelopment.
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