奥沙利铂
卡培他滨
医学
伊立替康
腹腔化疗
内科学
肿瘤科
癌症
结直肠癌
卵巢癌
作者
Niels A.D. Guchelaar,Marion W Tops-Welten,Pieter van der Sluis,Bo Jan Noordman,Stijn L.W. Koolen,Sjoerd M. Lagarde,Grard A. P. Nieuwenhuijzen,Micha J. de Neijs,Irene E G van Hellemond,Misha Luyer,Geert-Jan Creemers,Ignace H. J. T. de Hingh,Bianca Mostert,Bas P. L. Wijnhoven,Ron H.J. Mathijssen
标识
DOI:10.1016/j.biopha.2025.118491
摘要
Administration of 3-weekly CBIP irinotecan concomitant to systemic CAPOX was well tolerated at 75 mg in patients with gastric cancer and peritoneal metastases. Giving its promising clinical outcomes and the safety profile, CBIP of irinotecan provides a potential new treatment modality. A phase II study will commence to assess its feasibility and efficacy.
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