[Effects of transcutaneous electrical acupoint stimulation on the postoperative sleep quality and inflammatory factors in frail elderly patients].

To observe the effects of transcutaneous acupoint stimulation (TEAS) on sleep quality and inflammatory factor in frail elderly patients undergoing laparoscopic colorectal cancer surgery.A total of 100 frail elderly patients undergoing elective laparoscopic colorectal cancer surgery were randomly divided into an observation group and a control group, 50 cases in each one. Patients in the observation group received TEAS, 30 min before surgery until the end of surgery, at 18:00 on the day of surgery and on the 1st, 2nd and 3rd day after surgery (30 min each time). TEAS was delivered at bilateral Neiguan (PC 6), Shenmen (HT 7) and Hegu (LI 4). The disperse-dense wave of 2 Hz/100 Hz was selected, and the maximal stimulation intensity depended on patient's tolerance. The operation procedure in the control group was same as the observation group, but without electric stimulation exerted. The 1st day before surgery and on the 1st, 3rd and 7th day after surgery, the scores of Pittsburgh sleep quality index (PSQI) and Athens insomnia scale (AIS), as well as the serum levels of C reactive protein (CRP) and interleukin-6 (IL-6) were observed in the patients of two groups. At 24 h, 48 h and 72 h after surgery, the score of pain visual analogue scale (VAS) was recorded in the two groups, as well as the pressing times of analgesic pump and the usage of flurbiprofen axetil during analgesic stage. The occurrence of post operative adverse reactions was observed in the patients of two groups.On the 1st and 3rd day after surgery, except the usage of hypnotic drug scores, the scores of each item and the total scores of PSQI, as well as AIS scores were all increased in the two groups compared with those of 1 day before surgery (P<0.05); and the scores in the observation group were lower than those in the control group (P<0.05). On the 7th day after surgery, the scores of each item and the total scores of PSQI, and AIS scores were not different statistically in comparison between the two groups (P>0.05). On the 1st, 3rd and 7th day after surgery, serum levels of CRP and IL-6 were all increased in the patients of two groups when compared with those of 1 day before surgery (P<0.05), serum levels CRP and IL-6 in the patients of the observation group were lower than those of the control group (P<0.05). The VAS scores of 24 h, 48 h and 72 h after surgery, the pressing times of analgesic pump, the frequency and dosage of the remedies were not different statistically between the two groups (P>0.05).TEAS can effectively improve sleep quality and reduce inflammatory reaction in frail elderly patients undergoing laparoscopic colorectal cancer surgery.目的：观察经皮穴位电刺激（TEAS）对行腹腔镜结直肠癌手术的老年衰弱患者术后睡眠质量及血清炎性因子的影响。方法：将100例行腹腔镜结直肠癌手术的老年衰弱患者随机分为观察组和对照组，每组50例。观察组予TEAS，于术前30 min至术毕，手术当天及术后第1、2、3天18:00（每次30 min）连接电子针疗仪刺激双侧内关、神门及合谷，疏密波，频率2 Hz/100 Hz，刺激强度为患者能耐受的最大值。对照组操作同观察组，但不予电刺激。观察两组患者术前1 d，术后1、3、7 d 匹兹堡睡眠质量指数（PSQI）、阿森斯失眠量表（AIS）评分及血清C反应蛋白（CRP）、白细胞介素-6（IL-6）含量，记录两组患者术后24、48、72 h疼痛视觉模拟量表（VAS）评分，镇痛期间镇痛泵按压次数及镇痛药物氟比洛芬酯的使用情况，观察患者术后不良反应的发生情况。结果：术后1 d和术后3 d，除催眠药物使用情况评分外，两组患者PSQI各项评分及总分、AIS评分均较术前1 d升高（P<0.05），观察组低于对照组（P<0.05）；术后7 d，两组患者PSQI各项评分及总分、AIS评分比较，差异无统计学意义（P>0.05）。术后1、3、7 d，两组患者血清CRP、IL-6含量均较术前1 d升高（P<0.05），观察组患者血清CRP、IL-6含量低于对照组（P<0.05）。两组患者术后24、48、72 h VAS评分、镇痛泵按压次数、补救用药次数及剂量比较，差异均无统计学意义（P>0.05）。结论：TEAS可改善行腹腔镜结直肠癌手术的老年衰弱患者术后睡眠质量，降低炎性反应。.