CircGLIS3 Regulates the Proliferation and Apoptosis of Bovine Intramuscular Preadipocytes via the miR-21-3p/PDPK1/AKT Axis

. In vivo overexpression of circGLIS3 in mouse skeletal muscle increased PDGFRα- and Pref-1-positive preadipocyte populations. This study elucidates the molecular mechanism by which the circGLIS3/miR-21-3p/PDPK1/Akt axis regulates bovine preadipocyte proliferation and apoptosis, thereby providing significant theoretical insights into bovine IMF deposition.