Bladder Volume Monitoring Using Electrical Impedance Tomography With Simultaneous Multi-Tone Tissue Stimulation and DFT-Based Impedance Calculation Inside an FPGA

电阻抗断层成像 电阻抗 反问题 电子工程 现场可编程门阵列 断层摄影术 生物医学工程 计算机科学 材料科学 物理 工程类 数学 电气工程 光学 计算机硬件 数学分析
作者
Bruno M. G. Rosa,Guang Yang
出处
期刊:IEEE Transactions on Biomedical Circuits and Systems [Institute of Electrical and Electronics Engineers]
卷期号:14 (4): 775-786 被引量:30
标识
DOI:10.1109/tbcas.2020.3008831
摘要

In this article, a novel method for measuring the volume of the urinary bladder non-invasively is presented that relies on the principles dictated by Electrical Impedance Tomography (EIT). The electronic prototype responsible for injecting innocuous electrical currents to the lower abdominal region and measuring the developed voltage levels is fully described, as well as the computational models for resolution of the so-called Forward and Inverse Problems in Imaging. The simultaneous multi-tone injection of current provided by a high performance Field Programmable Gate Array (FPGA), combined with impedance estimation by the Discrete Fourier Transform (DFT) constitutes a novelty in Urodynamics with potential to monitor continuously the intravesical volume of patients in a much faster and comfortable way than traditional transurethral catheterization methods. The resolution of the Inverse Problem is performed by the Gauss-Newton method with Laplacian regularization, allowing to obtain a sectional representation of the volume of urine encompassed by the bladder and surrounding body tissues. Experimentation has been carried out with synthetic phantoms and human subjects with results showing a good correlation between the levels of abdominal admittivity acquired by the EIT system and the volume of ingested water.
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