Total magnetic resonance imaging burden of cerebral small vessel diseases and its application

Imaging findings of cerebral small vessel diseases (CSVD) include white matter lesions, enlarged perivascular spaces, lacunar infarcts and cerebral microbleeds. These imaging markers often appear at the same time. In recent years, the small vessel diseases was proposed by combining the different magnetic resonance imaging (MRI) markers into one measure of CSVD, so that we can capture all the brain damage from CSVD more accurately through the evaluation of total MRI burden. This paper reviews the research progress of total small vessel diseases score and its application. Key words: Cerebral small vessel disease; Neuroimaging; Cognitive disorders; Total magnetic resonance imaging burden