Experimental Studies of Geroprotective and Anti-Aging Effects of Chemical Compounds of Portulaca oleracea L. (Review)

The analysis presented in the review of publications shows that extract of Portulaca oleracea L. or its individual components (polysaccharides, oleracea, alkaloids tetrahydroisoquinoline operatein E) is able to increase the lifespan of laboratory animals, to activate telomerase and increase telomere length, and to provide antioxidant and antiosteoclastogenic impact. Various neuroprotective effects (improvement of memory and learning ability, inhibition of acetylcholinesterase, protection of dopaminergic neurons, improvement of motor functions, etc.) are of interest for the prevention of syndromes associated with age-related degradation of the nervous system such as Alzheimer’s and Parkinson’s diseases. In addition, regular consumption of vegetable portulaca in food leads to a decrease in the percentage of cancer and cardiovascular diseases, which also directly provides an increase in the average life expectancy of the population.