非对映体
对映选择合成
立体专一性
化学
分析物
组合化学
计算化学
材料科学
纳米技术
有机化学
色谱法
催化作用
出处
期刊:Methods in molecular biology
日期:2019-01-01
卷期号:: 1-33
被引量:14
标识
DOI:10.1007/978-1-4939-9438-0_1
摘要
Stereospecific recognition of chiral molecules plays an important role in nature as the basis of the interaction of chiral bioactive compounds with the chiral target structures. In separation sciences such as chromatographic and capillary electromigration techniques, interactions between chiral analytes and chiral selectors, i.e., the formation of transient diastereomeric complexes in thermodynamic equilibria, are the basis for chiral separations. Due to the large structural variety of chiral selectors, different structural features contribute to the overall chiral recognition process. This introductory chapter briefly summarizes the present understanding of the structural enantioselective recognition processes for various types of chiral selectors.
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