New Synthesis Process of 2-Thiopheneethylamine

2-Thienylacetaldehyde was synthesised by oxidation of 2-thienylethanol with PCC(Pyridinium chlorochromate)/SiO2,without purification and was further converted to 2-thienylacetaldoxime through reaction with hydroxylamine hydrochloride.Finally,2-thiopheneethylamine was obtained by the reduction of 2-thienylacetaldoxime with NaBH4-CuSO4-amberlyst-15.The overall yield of this process for 2-thiopheneethylamine was about 76.5%.