Objective To evaluate the feasibility,safety and validity of the early enteral nutrition in severe acute pancreatitis(SAP).Methods 15 patients of SAP during April 2002 to June 2003 received early enteral nutrition through naso-jejunal tube.The nutrition immune index and the rates of complications were analyzed.Results On 2-3 days after nutrition tube placed to stomach,the tube heads in 11 cases reached the jejunum automatically,while 3 cases needed the help of X-ray and 1 case needed the help of gastroscopy.All of 15 cases tolerated the enteral nutrition well,and there was no relapse of SAP.The nutrition and immune measurement were improved after 2 weeks enteral nutrition,without infection of pancreatic necrosis.Conclusions The early enteral nutrition through naso-jejunal tube is safe,efficient and feasible in severe acute pancreatitis.Early enteral nutrition can improve the nutrition,immune function and prognosis.