Enterococcus faecalis commensals of the intestinal tract of human and animals and is an important opportunistic pathogen.Enterococcus have emerged as a major cause of nosocomial infections because of antibiotcswidely used and animal feed added in.Control and therapy of an Enterococcus faecalis clinic become more and more difficult because it has special mechanisms of acquired drug resistance and some virulence factors.This study progress focuses on the biological characteristics of Enterococcus faecalis,pathogenic mechanisms,antibiotic resistance,laboratory diagnosis and treatment.