Therapeutic options for patients with hepatocellular carcinoma (HCC) are rapidly expanding. Such treatments include liver resection, liver transplantation, liver-directed therapies (such as chemoembolization and radiofrequency ablation), and systemic chemotherapy with sorafenib (JW Gastroenterol Jul 23 2008). Given the high degree of variability in how HCC affects patients, reliable data on survival of those with untreated …