Objectives:To explore on the clinical effect of lactobacillus vagina capsule on the treatment of recurrent vulvovaginal candidiasis.Methods:Two hundred and eighty-five patients with recurrent vulvovaginal candidiasis were selected and divided into the study group(142 cases) and the control group(143 cases).The study group were administered with Nysfungin Vaginal Suppositories,1 tablets daily,placed in the deep vagina for 7 days.One week before and after menstrum,two of lactobacillus vagina capsules were placed in deep vagina daily for 7 days.Clinical symptoms,laboratory test results and recurrence rates were observed after week 1,4,8 medication.Results:The overall efficiency rate for the study group and the control qroup after week 1 was 98.5% and 97.9% respectively,the difference being not significant(P0/05).The recurrence rate for the study and control group after week 8 was 1.40% and 8.39% respectively,the difference being significant(P0.05).Conclusion:Nysfungin Vaginal Suppositories combined with lactobacillus vagina capsule indicates satisfactory effects and low recurrence rate in the treatment of vulvovaginal candidiasis.