Study on anti-fatigue effect of RADIX ET RHIZOMA GINSENG and RADIX NOTOGINSENG extracts in mice.

[Objective] To explore the anti-fatigue effect of RADIX ET RHIZOMA GINSENG and RADIX NOTOGINSENG extracts in mice,so as to provide reference for further development and application of RADIX ET RHIZOMA GINSENG and RADIX NOTOGINSENG extracts.[Method] Divided into four batches,forty-eight mice in each batch were subdivided into four groups like control group(CK),50,100 and 300 mg/kg medicine group.The loaded swimming duration and content of serum urea nitrogen,blood lactate and hepatic glycogen of mice in each test group were determined respectively 30 days later.[Result] In comparison with control group,mice in the group of 100 and 300 mg/kg medicine group were significantly longer in loaded swimming duration(P0.01),and higher in content of hepatic glycogen(P0.01;P0.05),whereas was lower in content of serum urea nitrogen(P0.01;P0.05).Contents of blood lactate in mice in 100 and 300 mg/kg medicine group after exercise were significantly lower than those in control group(P0.01;P0.05).[Conclusion] RADIX ET RHIZOMA GINSENG and RADIX NOTOGINSENG extracts are provided with efficacy of alleviating physical fatigue.