Management of cleft palate among patients with Pierre Robin sequence

Pierre Robin Sequence（PRS）is a congenital craniofacial anomaly featured by micrognathia, glossoptosis, and upper airway obstruction. Cleft palate occurs in over 3/4 of patients with PRS. The wide U-shape cleft and airway dysfunction brings challenges to clinical management. Currently, disputes exist on the treatment protocol and prognosis of cleft palate management among patients with PRS. This review focused on the deformity features, intervention timing, technique selection, airway support, and outcome evaluation of cleft palate among patients with PRS, aiming to provide reference to further evolution in the management of PRS-related cleft palate.