CYP2E1
药理学
对乙酰氨基酚
下调和上调
氧化应激
细胞凋亡
肝损伤
毒性
化学
刺
H&E染色
免疫印迹
医学
免疫组织化学
内科学
生物化学
细胞色素P450
酶
航空航天工程
工程类
基因
作者
Hongfei Wang,Jia-Shuang Xu,Ke Zong,Zhiwei Liang,Renfeng Li,Jianfeng Xue,Jing Ding,Longshuan Zhao
标识
DOI：10.1016/j.ecoenv.2023.115810
摘要
Jujuboside B (JuB) is the main bioactive saponin component of Chinese anti-insomnia herbal medicine Ziziphi Spinosae Semen, which has been reported to possess varied pharmacological functions. Even though it has been traditionally used to treat inflammation- and toxicity-related diseases, the effects of JuB on acetaminophen (APAP) overdose-induced hepatotoxicity have not been determined yet.
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