Multivariate metal–organic frameworks generated through post-synthetic modification: impact and future directions

conditions and the focus on generating MOFs with single ligand and metal. To surpass these limitations, researchers have established strategies to generate multivariate (MTV) MOF structures incorporating more than one ligand/metal into the crystal lattice. MTV-MOFs have demonstrated enhanced properties by virtue of the additional functionalities incorporated within their structures. One approach to developing MTV-MOFs is through post-synthetic modification (PSM), where new functionalities are introduced after the initial synthesis, thereby achieving the enhanced properties of MTV-MOFs even in cases where the new functionalities are incompatible with MOF synthesis.