牛磺酸
线粒体生物发生
糖酵解
氧化磷酸化
线粒体
乳酸脱氢酶
琥珀酸脱氢酶
苹果酸脱氢酶
内科学
柠檬酸合酶
内分泌学
化学
生物
生物化学
新陈代谢
酶
医学
氨基酸
作者
Wenting An,Zhiqing Huang,Zhengyu Mao,Tianlei Qiao,Gang Jia,Hua Zhao,Guangmang Liu,Xiaoling Chen
标识
DOI:10.1021/acs.jafc.3c01163
摘要
This study investigated the effects of dietary supplementation with taurine (TAU) on the meat quality, muscle fiber type, and mitochondrial function of finishing pigs. The results demonstrated that TAU significantly increased the a* value while decreasing b*45 min, L*24 h, and drip loss24 h and drip loss48 h in the longissimus dorsi (LD) muscle. Dietary supplemented with TAU reduced the content of lactate and the glycolytic potential (GP) in the LD muscle. Dietary supplemented with TAU enhanced the oxidative fiber-related gene expression as well as increased succinic dehydrogenase and malate dehydrogenase activities while reducing lactate dehydrogenase activity. Furthermore, dietary supplementation with TAU increased the contents of mtDNA and ATP and mitochondrial function-related gene expression. Moreover, TAU enhanced the mRNA expressions of calcineurin (CaN) and nuclear factor of activated T cells c1 (NFATc1) and protein expressions of CNA and NFATc1. The results indicate that dietary TAU supplementation improves meat quality and mitochondrial biogenesis and function and promotes muscle fiber-type conversion from the glycolytic fiber to the oxidative fiber via the CaN/NFATc1 pathway.
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